Q: How effective is Zyban?

A: Zyban approximately doubles the chances of quitting smoking at 3 months from quit date. This drops back a little at 1 year from stopping. Zyban may reduce weight gain from stopping smoking, while it is being taken, although weight gain can occur when Zyban is stopped 4.

Q: How should I take Zyban?

A: Take Zyban exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label. Zyban can be taken with or without food. Do not crush, chew, or break the extended-release tablet (Wellbutrin SR, Wellbutrin XL, Zyban SR). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Q: What happens if I miss a dose?

A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Q: What happens if I overdose?

A: Seek emergency medical attention if you think you have used too much Zyban. Symptoms of a Zyban overdose may include seizures, muscle stiffness, hallucinations, fainting, fast or uneven heartbeat, shallow breathing, heart failure, or coma.

Q: What other drugs will affect Zyban?

A: Do not take Zyban if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), or tranylcypromine (Parnate) in the last 14 days. There are many other drugs that can affect Zyban. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.